Uncertainty Assessment and False Discovery Rate Control in High-Dimensional Granger Causal Inference

نویسندگان

  • Aditya Chaudhry
  • Pan Xu
  • Quanquan Gu
چکیده

Causal inference among high-dimensional time series data proves an important research problem in many fields. While in the classical regime one often establishes causality among time series via a concept known as “Granger causality,” existing approaches for Granger causal inference in high-dimensional data lack the means to characterize the uncertainty associated with Granger causality estimates (e.g., p-values and confidence intervals). We make two contributions in this work. First, we introduce a novel asymptotically unbiased Granger causality estimator with corresponding test statistics and confidence intervals to allow, for the first time, uncertainty characterization in high-dimensional Granger causal inference. Second, we introduce a novel method for false discovery rate control that achieves higher power in multiple testing than existing techniques and that can cope with dependent test statistics and dependent observations. We corroborate our theoretical results with experiments on both synthetic data and real-world climatological data.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The False Discovery Rate in Simultaneous Fisher and Adjusted Permutation Hypothesis Testing on Microarray Data

Background and Objectives: In recent years, new technologies have led to produce a large amount of data and in the field of biology, microarray technology has also dramatically developed. Meanwhile, the Fisher test is used to compare the control group with two or more experimental groups and also to detect the differentially expressed genes. In this study, the false discovery rate was investiga...

متن کامل

Global Testing and Large-Scale Multiple Testing for High-Dimensional Covariance Structures

Driven by a wide range of contemporary applications, statistical inference for covariance structures has been an active area of current research in high-dimensional statistics. This paper provides a selective survey of some recent developments in hypothesis testing for high-dimensional covariance structures, including global testing for the overall pattern of the covariance structures and simul...

متن کامل

Hierarchical False Discovery Rates: Large-scale Inference for Plate-based High-throughput Phenotyping Methods by

Hierarchical False Discovery Rates: Large-scale Inference for Plate-based High-throughput Phenotyping Methods Hannes Bretschneider 2011 This thesis introduces Hierarchical false discovery rates, a new semi-parametric Bayesian method for the detection of causal links between a genotype and phenotype in high-throughput phenotypic studies. Hierarchical false discovery rates are designed for plate-...

متن کامل

Elastic-Net Copula Granger Causality for Inference of Biological Networks

AIM In bioinformatics, the inference of biological networks is one of the most active research areas. It involves decoding various complex biological networks that are responsible for performing diverse functions in human body. Among these networks analysis, most of the research focus is towards understanding effective brain connectivity and gene networks in order to cure and prevent related di...

متن کامل

On Causality Inference in Time Series

Causality discovery has been one of the core tasks in scientific research since the beginning of human scientific history. In the age of data tsunami, the task could involve millions of variables, which cannot be achieved feasibly by human. However, the causal discovery using artificial intelligence and statistical techniques in non-experimental settings faces several challenges. In this work, ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017